Undi RB, Ahsan N, Larabee JL, Darlene-Reuter N, Papin J, Dogra S, Hannafon BN, Bronze MS, Houchen CW, Huycke MM, Ali N. Blocking of doublecortin-like kinase 1-regulated SARS-CoV-2 replication cycle restores cell signaling network. J Virol. 2023 Nov 30;97(11):e0119423. doi: 10.1128/jvi.01194-23. Epub 2023 Oct 20. PMID: 37861336; PMCID: PMC10688311. https://journals.asm.org/doi/full/10.1128/jvi.01194-23?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org
Dogra S, Elayapillai SP, Qu D, Pitts K, Filatenkov A, Houchen CW, Berry WL, Moxley K, Hannafon BN. Targeting doublecortin-like kinase 1 reveals a novel strategy to circumvent chemoresistance and metastasis in ovarian cancer. Cancer Lett. 2023 Dec 1;578:216437. doi: 10.1016/j.canlet.2023.216437. Epub 2023 Oct 12. PMID: 37838282; PMCID: PMC10872611. https://www.sciencedirect.com/science/article/pii/S0304383523003889?via%3Dihub
Han Z, MacCuaig WM, Gurcan MN, Claros-Sorto J, Garwe T, Henson C, Holter-Chakrabarty J, Hannafon B, Chandra V, Wellberg E, McNally LR. Dynamic 2-deoxy-D-glucose-enhanced multispectral optoacoustic tomography for assessing metabolism and vascular hemodynamics of breast cancer. Photoacoustics. 2023 Jul 9;32:100531. doi: 10.1016/j.pacs.2023.100531. PMID: 37485041; PMCID: PMC10362308. https://www.sciencedirect.com/science/article/pii/S2213597923000848?via%3Dihub
Burrows K, Figueroa-Hall L, Stewart J, Alarbi A, Kuplicki R, Hannafon B, Tan C, Risbrough V, McKinney B, Ramesh R, Victor T, Aupperle R, Savitz J, Teague K, Khalsa S, Paulus M. Exploring the role of neuronal-enriched extracellular vesicle miR-93 and interoception in major depressive disorder. Res Sq [Preprint]. 2023 Jun 16:rs.3.rs-2813878. doi: 10.21203/rs.3.rs-2813878/v1. PMID: 37398092; PMCID: PMC10312986. https://www.researchsquare.com/article/rs-2813878/v1
Burrows, K., Figueroa-Hall, L. K., Alarbi, A. M., Stewart, J. L., Kuplicki, R., Tan, C., Hannafon, B. N., Ramesh, R., Savitz, J., Khalsa, S., Teague, T. K., Risbrough, V. B., & Paulus, M. P. (2023). Association between inflammation, reward processing, and ibuprofen-induced increases of miR-23b in astrocyte-enriched extracellular vesicles: A randomized, placebo-controlled, double-blind, exploratory trial in healthy individuals. Brain, Behavior, & Immunity - Health, 27, 100582. https://doi.org/https://doi.org/10.1016/j.bbih.2022.100582
Hannafon, B. N. (2021). Involvement of the Tumor Microenvironment in the Pathogenesis of Breast Cancer. Am J Pathol, 191(8), 1328-1329. https://doi.org/10.1016/j.ajpath.2021.05.012
Dogra, S., & Hannafon, B. N. (2021). Breast Cancer Microenvironment Cross Talk through Extracellular Vesicle RNAs. Am J Pathol, 191(8), 1330-1341. https://doi.org/10.1016/j.ajpath.2021.03.014
Xu, Y. F., Xu, X., Bhandari, K., Gin, A., Rao, C. V., Morris, K. T., Hannafon, B. N., & Ding, W. Q. (2021). Isolation of extra-cellular vesicles in the context of pancreatic adenocarcinomas: Addition of one stringent filtration step improves recovery of specific microRNAs. PLoS One, 16(11), e0259563. https://doi.org/10.1371/journal.pone.0259563
Xu, Y. F., Xu, X., Gin, A., Nshimiyimana, J. D., Mooers, B. H. M., Caputi, M., Hannafon, B. N., & Ding, W. Q. (2020). SRSF1 regulates exosome microRNA enrichment in human cancer cells. Cell Commun Signal, 18(1), 130. https://doi.org/10.1186/s12964-020-00615-9
Xu, Y. F., Hannafon, B. N., Khatri, U., Gin, A., & Ding, W. Q. (2019). The origin of exosomal miR-1246 in human cancer cells. RNA Biol, 16(6), 770-784.
Hannafon, B. N., Gin, A. L., Xu, Y. F., Bruns, M., Calloway, C. L., & Ding, W. Q. (2019). Metastasis-associated protein 1 (MTA1) is transferred by exosomes and contributes to the regulation of hypoxia and estrogen signaling in breast cancer cells. Cell Commun Signal, 17(1), 13. https://doi.org/10.1186/s12964-019-0325-7
Hannafon, B. N., & Ding, W. Q. (2019). Functional Role of miRNAs in the Progression of Breast Ductal Carcinoma in Situ. Am J Pathol, 189(5), 966-974. https://doi.org/10.1016/j.ajpath.2018.06.025
Hannafon, B. N., Cai, A., Calloway, C. L., Xu, Y. F., Zhang, R., Fung, K. M., & Ding, W. Q. (2019). miR-23b and miR-27b are oncogenic microRNAs in breast cancer: evidence from a CRISPR/Cas9 deletion study. BMC Cancer, 19(1), 642. https://doi.org/10.1186/s12885-019-5839-2
Hannafon, B. N., & Ding, W. Q. (2018). miRNAs as Biomarkers for Predicting the Progression of Ductal Carcinoma in Situ. Am J Pathol, 188(3), 542-549. https://doi.org/10.1016/j.ajpath.2017.11.003
Jiao, Y., Watts, T., Xue, J., Hannafon, B., & Ding, W. Q. (2018). Sorafenib and docosahexaenoic acid act in synergy to suppress cancer cell viability: a role of heme oxygenase 1. BMC Cancer, 18(1), 1042. https://doi.org/10.1186/s12885-018-4946-9
Xu, Y. F., Hannafon, B. N., Zhao, Y. D., Postier, R. G., & Ding, W. Q. (2017). Plasma exosome miR-196a and miR-1246 are potential indicators of localized pancreatic cancer. Oncotarget, 8(44), 77028-77040. https://doi.org/10.18632/oncotarget.20332
Xu, Y. F., Hannafon, B. N., & Ding, W. Q. (2017). microRNA regulation of human pancreatic cancer stem cells. Stem Cell Investig, 4, 5. https://doi.org/10.21037/sci.2017.01.01
Jiao, Y., Hannafon, B. N., Zhang, R. R., Fung, K. M., & Ding, W. Q. (2017). Docosahexaenoic acid and disulfiram act in concert to kill cancer cells: a mutual enhancement of their anticancer actions. Oncotarget, 8(11), 17908-17920. https://doi.org/10.18632/oncotarget.14702
Jiao, Y., Hannafon, B. N., & Ding, W. Q. (2016). Disulfiram's Anticancer Activity: Evidence and Mechanisms. Anticancer Agents Med Chem, 16(11), 1378-1384. https://doi.org/10.2174/1871520615666160504095040
Hannafon, B. N., Trigoso, Y. D., Calloway, C. L., Zhao, Y. D., Lum, D. H., Welm, A. L., Zhao, Z. J., Blick, K. E., Dooley, W. C., & Ding, W. Q. (2016). Plasma exosome microRNAs are indicative of breast cancer. Breast Cancer Res, 18(1), 90. https://doi.org/10.1186/s13058-016-0753-x
Wang, S., Hannafon, B. N., Lind, S. E., & Ding, W. Q. (2015). Zinc Protoporphyrin Suppresses β-Catenin Protein Expression in Human Cancer Cells: The Potential Involvement of Lysosome-Mediated Degradation. PLoS One, 10(5), e0127413. https://doi.org/10.1371/journal.pone.0127413
Hannafon, B. N., & Ding, W. Q. (2015). Cancer stem cells and exosome signaling. Stem Cell Investig, 2, 11. https://doi.org/10.3978/j.issn.2306-9759.2015.05.02
Hannafon, B. N., Carpenter, K. J., Berry, W. L., Janknecht, R., Dooley, W. C., & Ding, W. Q. (2015). Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA). Mol Cancer, 14, 133. https://doi.org/10.1186/s12943-015-0400-7
Zhang, S., Xue, J., Zheng, J., Wang, S., Zhou, J., Jiao, Y., Geng, Y., Wu, J., Hannafon, B. N., & Ding, W. Q. (2015). The superoxide dismutase 1 3'UTR maintains high expression of the SOD1 gene in cancer cells: The involvement of the RNA-binding protein AUF-1. Free Radic Biol Med, 85, 33-44. https://doi.org/10.1016/j.freeradbiomed.2015.04.012
Xue, J., Moyer, A., Peng, B., Wu, J., Hannafon, B. N., & Ding, W. Q. (2014). Chloroquine is a zinc ionophore. PLoS One, 9(10), e109180. https://doi.org/10.1371/journal.pone.0109180
Wang, S., Hannafon, B. N., Wolf, R. F., Zhou, J., Avery, J. E., Wu, J., Lind, S. E., & Ding, W. Q. (2014). Characterization of docosahexaenoic acid (DHA)-induced heme oxygenase-1 (HO-1) expression in human cancer cells: the importance of enhanced BTB and CNC homology 1 (Bach1) degradation. J Nutr Biochem, 25(5), 515-525. https://doi.org/10.1016/j.jnutbio.2013.12.011
Xue, J., Wang, S., Wu, J., Hannafon, B. N., & Ding, W. Q. (2013). Zinc at sub-cytotoxic concentrations induces heme oxygenase-1 expression in human cancer cells. Cell Physiol Biochem, 32(1), 100-110. https://doi.org/10.1159/000350128
Wang, S., Avery, J. E., Hannafon, B. N., Lind, S. E., & Ding, W. Q. (2013). Zinc protoporphyrin suppresses cancer cell viability through a heme oxygenase-1-independent mechanism: the involvement of the Wnt/β-catenin signaling pathway. Biochem Pharmacol, 85(11), 1611-1618. https://doi.org/10.1016/j.bcp.2013.03.011
Hannafon, B. N., & Ding, W. Q. (2013). Intercellular communication by exosome-derived microRNAs in cancer. Int J Mol Sci, 14(7), 14240-14269. https://doi.org/10.3390/ijms140714240
Wang, S., Hannafon, B. N., Zhou, J., & Ding, W. Q. (2013). Clofibrate induces heme oxygenase 1 expression through a PPARα-independent mechanism in human cancer cells. Cell Physiol Biochem, 32(5), 1255-1264. https://doi.org/10.1159/000354524
Hannafon, B. N., Sebastiani, P., de las Morenas, A., Lu, J., & Rosenberg, C. L. (2011). Expression of microRNA and their gene targets are dysregulated in preinvasive breast cancer. Breast Cancer Res, 13(2), R24. https://doi.org/10.1186/bcr2839
Liu, T., Hannafon, B., Gill, L., Kelly, W., & Benbrook, D. (2007). Flex-Hets differentially induce apoptosis in cancer over normal cells by directly targeting mitochondria. Mol Cancer Ther, 6(6), 1814-1822. https://doi.org/10.1158/1535-7163.Mct-06-0279
Benbrook, D. M., Kamelle, S. A., Guruswamy, S. B., Lightfoot, S. A., Rutledge, T. L., Gould, N. S., Hannafon, B. N., Dunn, S. T., & Berlin, K. D. (2005). Flexible heteroarotinoids (Flex-Hets) exhibit improved therapeutic ratios as anti-cancer agents over retinoic acid receptor agonists. Invest New Drugs, 23(5), 417-428. https://doi.org/10.1007/s10637-005-2901-5